Carboxytherapy

Aesthetic & Dermatology

What is carbon dioxide therapy ?

Carbon dioxide therapy (CDT) is a procedure which is very similar to mesotherapy. It consists of intradermal or subcutaneous injections of medical grade CO2 using 30 G needles. CO2 insufflation has been widely used in the last 8 years in South America and in particular in Brazil for cosmetic purposes, such as stretch marks, cellulite, localized adiposities and under-eye dark circles, in combination with other minimally invasive aesthetic procedures. The low morbidity, high level of patient tolerance and minimal side effects makes it a very interesting technique in our battery of face and body rejuvenation techniques, with a high level of patient satisfaction.

Carboxytherapy has also been used in the medical field for over 80 years, in Angiology, Phlebology, Endocrinology, and Dermatology to treat diseases: ischemic lower limbs pathologies, diabete ulcers, microvascularization diseases (Raynaud phenomenon ...). Carboxytherapy has also been used recently on Psoriasis disease with interesting results

Mechanism of action

Vasodilatation The first effects following CO2 injection is a strong vasodilatation, a blood flow increase and a higher pO2 in the treated area.

The Bohr effect Local oxygen release is improved because of the Bohr effect. The Bohr effect describes the tendency of haemoglobin to have less affinity for oxygen when the blood concentration of CO2 is increased. This lower affinity leads the haemoglobin to release the oxygen better in superficial tissues and muscles. CO2 is quickly converted to bicarbonates and H+ acid in presence of the carbonic anhydrase enzyme.

CO2 + H2O --> H+ + HCO3-

This reaction causes the tissue’s pH to become acidic with even more dissociation of O2 from haemoglobin, allowing the tissue to become even more oxygenated.

 

 

 

 

 

 

 

Stimulation of collagen synthesis
A 2008 Brazilian study* showed a reorganization of collagen fibers following intradermal injections of carbon dioxide and demonstrated that the CO2 is capable of increasing the collagen turnover: a trauma to the dermis launches a healing process with collagen synthesis. CO2 improves the process by first, increasing neovascularization with more healing substances and factors to be on site. In second, it releases more oxygen around and in the healing area, improving the recovery phase.

Neo-angiogenesis effect
The first experiments in the 1930s consisted of injecting CO2 into the leg of a frog. They have shown a strong vasodilatation, associated with the creation of new capillaries.

Receptor activation and lipolysis cascading improvement
The pressure receptors are stimulated by CO2 injections. Cascading reactions improve the lipolysis process in the injected areas. CO2 is improving the natural lipolysis capabilities of the body

Indications of CO2 therapy

Aesthetic indications can be divided in 2 main groups:

Group 1 is dealing with fat/cellulite.
Group 2 is targeting collagen, blood flow and skin oxygenation.

Schematically fat indications require deep injections: subcutaneous injections

 

 

 

 

 

 

 

and rejuvenation indications need superficial intradermal injections

 

 

 

 

 

 

 

Common medical indications
 for CO2 therapy

Recent scars and acne scars

Alone or combined with other techniques: fillers, lasers… in the medical treatment of burns, traumatic scars, of post surgery scars

psoriasis

 

Raynaud's phenomenon

CO2 therapy as effects on the Raynaud’s syndrom

ulcers

Ulcers with a vascular (arterial) component are medical indications.

Lower limbs ischemic diseases

Ischemic pathology with a micro vascularisation side is a medical indication

Lymphoedema &
Lymphatic diseases

Carboxytherapy acts on the microcirculation at the level of metarterioles, arterioles and precapillary shpincteres by increasing tissue flow velocity and consequently, by improving lymphatic drainage

Common aesthetic indications
 for CO2 therapy

cellulite skin appearance
(orange peel)

Alone or combined with other modalities such as massage, mesotherapy

Localized fat

Alone or combined with liposuction, Cellu-M6®, RF.

face wrinkles

Alone or combined with other procedures such as mesolift, HA/Botox® injections, LED, RF, lasers

eye wrinkles

Alone or combined with other procedures such as mesolift, fillers, RF, laser

under-eye dark circles

Alone or combined with other modalities: peelings…

skin laxity

Alone or combined with other procedures: laser, mechanical massage, mesotherapy, RF

old stretch marks

White stretch marks, drpessed stretch marks are good indications

hair loss

Although not proven by a specific study, better oxygenation may lead to a reduction of hair loss

 

PSORIASIS

 

 

 

 

 

STRETCHMARKS

 

 

 

 

 

 

Up & Left: before treatment - Up-Right: after 1 session Down: after 3 sessions

 

 

EYE REJUVENATION

 

 

 

 

 

3 different sessions - 30 cc/min - Monthly spaced.

 

All these image are property of the inventor of SKIN-Breath. These treatments have been peformed with the genuine Skin-breath, not copies. If you see these photos to illustrate other products, they are copyright violations.

 

Advantages od CO2 therapy

Disadvantages

No down-time

More studies need to be published to evaluate the technique in detail.

Very fast to perform procedures

MD need to hire a CO2 tank from a medical gas company - SKIN BREATH DOES NOT REQUIRE MD TO RENT BIG TANKS

Can be performed by a nurse under the supervision of the physician

Localized fat may require numerous sessions before both the patient and physician see the first results.

Almost no pain in most of the cases

Not FDA approved procedure

Low cost equipment

Some equipment are not CE medical approved therefore illegal to use in some countries.

Impressive results on stretch marks. Also impressive results on Psoriasis

 

Can be combined to other procedures

 

 

Advantages of Carboxytherapy

CO2 is not expensive. Equipment is easy to operate. Training is easy.

Advantages od CO2 therapy

Disadvantages

No down-time

More studies need to be published to evaluate the technique in detail.

Very fast to perform procedures

MD need to hire a CO2 tank from a medical gas company - SKIN BREATH DOES NOT REQUIRE MD TO RENT BIG TANKS

Can be performed by a nurse under the supervision of the physician

Localized fat may require numerous sessions before both the patient and physician see the first results.

Almost no pain in most of the cases

Not FDA approved procedure

Low cost equipment

Some equipment are not CE medical approved therefore illegal to use in some countries.

Impressive results on stretch marks. Also impressive results on Psoriasis

 

Can be combined to other procedures

 

 

Carboxytherapy是治疗的皮肤各种条件，包括妊娠纹，眼睛下面的脂肪和黑眼圈，以及脂肪雕塑门诊化妆品的程序。在治疗的基础上，不断交流，以取代氧气在人体内的二氧化碳。

程序
Carboxytherapy涉及注入二氧化碳气体，并下到皮肤下层。注射二氧化碳会使身体增加氧气流量，以消除该地区的二氧化碳。增加氧气流向受损面积开始恢复过程。

理论
妊娠纹，发生在皮肤时（中）层的胶原蛋白和皮肤破裂，由于破裂的皮肤伸展在怀孕期间和导致体重增加其他活动。胶原击穿叶不雅观，变色和皮肤皱纹，一些研究报告，描述性瘢痕组织的乐队。新成立的妊娠纹，或条纹，是红颜色的。年龄较大的条纹是白色。 Carboxytherapy减少妊娠纹，刺激新的胶原蛋白在皮肤的真皮层形成的外观。

处理
Carboxytherapy治疗，不要伤害，但觉得“有点怪。”病人可能会感到有些压力的二氧化碳注入，并扩大了妊娠纹，而妊娠纹可以感觉到有点痒。这两种影响减少在大约5分钟。由于瘢痕组织不包含神经，治疗时无痛苦，是用于治疗妊娠纹。一系列的治疗通常是必需的。

副作用
在注射部位的瘀伤是唯一的共同副作用carboxytherapy作用，各国还没有已知的程序的风险。

历史
该程序的发明，早在20世纪治疗周围动脉在手臂和腿部的大血管堵塞造成闭塞性疾病在法国的皇家温泉。中医在欧洲和南美洲延伸的疗法来治疗妊娠纹等皮肤疾病。过程是在美国使用的今天，以减少妊娠纹及其他目的，though它has没有受到美国Food和药品管理局批准for such治疗，根据医生联盟为注射Safety。也没有，说了同样的来源，是否有临床试验证明是有效的治疗。

 

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